KGO enzyme panels

Curated ketoglutarate-dependent oxygenases for scalable, selective, and sustainable biocatalysis

KGO enzyme panels

A focused collection of alpha-ketoglutarate-dependent oxygenases covering a versatile group of enzymes critical to a wide range of biochemical transformations.

Scalable & sustainable oxygenation chemistry

No Complex Systems Required.Para: KGOs are stable, easy to express, and capable of highly selective oxidative transformations hydroxylation, halogenation, desaturation, and ring formation under mild aqueous conditions. No P450 complexity, no cofactor headaches.

Curated enzyme panels for faster discovery

Generic panels mean low coverage and wasted screening rounds. Our KGO panels are assembled using computational prediction and active-site profiling — focused on your substrate class from the start.

Four Panels. Four Discovery Pathways.

Each panel is optimized for a specific chemistry space

AminoAcid KGO Panel

42 curated KGOs for targeted functionalization of canonical and non-canonical amino acids — purpose-built for peptide APIs, biomaterials, and advanced intermediates.

Example products:

trans-3-hydroxy-L-proline · 4-chloro-lysine · cis-3-hydroxy-L-pipecolic acid · 5-hydroxy-leucine

Best for: Pharma R&D, peptide chemistry, novel amino acid synthesis

Precision biocatalysis for natural product modification

With 38 curated KGOs, this panel enables selective oxyfunctionalization of fatty acids, terpenes, alkaloids, and steroids. Designed for innovation in flavours & fragrances, agrochemicals, and bioactive compounds.

Example products:

trans-3-hydroxy-L-proline · 4-chloro-lysine · cis-3-hydroxy-L-pipecolic acid · 5-hydroxy-leucine

Best for: Natural product chemistry, F&F, agro, bioactive discovery

Site-selective nucleic acid modification made accessible

This 22-enzyme panel unlocks precise modifications of nucleosides and nucleotides, enabling advanced tools for RNA therapeutics, synthetic biology, and molecular probes.

Example products:

5-formyluracil · 5-methyluridine · hydroxymethyluracil · modified nucleotides

Best for: RNA therapeutics, nucleic acid chemistry, biotech tools

Check out our other enzyme products

KGOs perform fascinating chemistry

I firmly believe KGOs can change the way we make chemistry. If you are interested in screening our KGO Enzyme Panel, let's have a chat.